Alzheimer's disease

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Suggestions of Fraud Rattle Alzheimer's Research Field

Investigation casts doubt on fundamental work from 2006

(Newser) - In the world of Alzheimer's research, it's a bombshell. A new investigation has raised allegations that landmark research conducted in 2006 was fabricated, reports NBC News . The journal Science is out with a report that casts serious doubt on the work of Sylvain Lesne of the University of...

Young Spinal Fluid Improves Memory in Older Mice
Fight Against Aging
Enters a 'Whole New Era'
NEW STUDY
May 17, 2022 12:09 PM CDT

Fight Against Aging Enters a 'Whole New Era'

Young spinal fluid is seen to improve memory in older mice, per new research

(Newser) - Researchers are heralding "a whole new era" in the search for Alzheimer's treatments, with a new study suggesting those treatments don't necessarily need to address damage in the brain. Tony Wyss-Coray of Stanford University previously showed infusions of blood from younger animals could reverse the effects of...

&#39;Vicious Cycle&#39; Involves Napping, Cognitive Decline
'Vicious Cycle' Involves
Napping, Alzheimer's
NEW STUDY
Mar 17, 2022 12:23 PM CDT

'Vicious Cycle' Involves Napping, Alzheimer's

Study suggests excessive daytime napping is associated with greater risk for the disease among older adults

(Newser) - Older adults who suddenly find themselves napping longer and more frequently during the day might want to have their brains checked. That's according to researchers at Brigham and Women's Hospital who explored a link between excessive daytime napping and Alzheimer's disease. They analyzed the duration and frequency...

Medicare Makes Big Decision on New Alzheimer's Drug

For now, it will limit Aduhelm coverage to those involved in a clinical trial

(Newser) - Medicare said Tuesday it will limit coverage of a $28,000-a-year Alzheimer’s drug whose benefits have been widely questioned , a major development in the nation’s tug-of-war over the fair value of new medicines that offer tantalizing possibilities but come with prohibitive prices. The initial determination from the Centers...

Maker Cuts Price of Alzheimer's Drug in Half

The medication wasn't catching on at more than $50K per year, Biogen says

(Newser) - Biogen is slashing the price of its Alzheimer's treatment in half, months after it debuted to widespread criticism over an initial cost that could reach $56,000 annually. The drugmaker said Monday that it will cut the wholesale acquisition cost of the drug by about 50% next month. That...

Death Raises New Concern Over Alzheimer's Drug

Critics say Aduhelm approval was rushed

(Newser) - Aduhelm, the Alzheimer’s drug approved this summer in a process that led some FDA advisers to quit , is the subject of new controversy. A 75-year-old woman in Canada participating in a clinical trial died in September after going to the hospital for a seizure, the New York Times reports....

Alzheimer's Vaccine Delivered via the Nose to Be Tested

The vaccine is intended to both prevent Alzheimer's and slow its progress

(Newser) - Dr. Howard Weiner has spent 20 years on research leading up to this moment: the "landmark first human trial" of an Alzheimer's disease nasal vaccine. Sixteen people ranging in age from 60 to 85 will get two doses over the course of two weeks at the Ann Romney...

Cabbies' 'Remarkable Brains' Help Alzheimer's Research

London drivers map routes during MRI scans

(Newser) - The brains of London cabdrivers aren't like other people's. Before they're hired, prospective drivers study the city's streets for years and memorize thousands of routes, the Washington Post reports. And it's not just a matter of remembering information long enough to pass the tests; human...

Cops: Wife Told Husband He Had Alzheimer&#39;s, Stole $600K
Cops: Wife Duped Husband for
Years, to the Tune of $600K
in case you missed it
Oct 31, 2021 8:45 AM CDT

Cops: Wife Duped Husband for Years, to the Tune of $600K

Donna Marino's spouse didn't have Alzheimer's but she made him think he did to control his money

(Newser) - For two decades, a Connecticut man says he let his wife handle virtually all of his finances for him, a move he apparently felt even more necessary once he was diagnosed with Alzheimer's. At least, he thought he'd been diagnosed with Alzheimer's. East Haven police say that'...

2 Health Care Systems Won't Use Aduhelm Yet

Cleveland Clinic, Mount Sinai wait for results of investigation into FDA approval process

(Newser) - Although a new drug for treating Alzheimer's cleared the Food and Drug Administration's approval process, a pair of large health systems say it has not cleared theirs. The Cleveland Clinic and Mount Sinai Health System in New York won't administer Aduhelm to patients until they have more...

FDA Approval of Alzheimer's Drug to Be Reviewed

Agency chief fears damage to public confidence in process

(Newser) - The acting head of the Food and Drug Administration wants the agency's inspector general to conduct an independent review of the agency's approval of a new drug to treat Alzheimer's. The approval process, which one outside adviser had called a "sham" as he resigned, has been...

FDA Walks Back Broad Alzheimer's Drug Advice

After criticism, agency says label will limit candidates to those with mild symptoms

(Newser) - After being widely criticized for approving the use of a new drug to treat all Alzheimer's patients, despite only limited evidence that it works, the Food and Drug Administration has stepped back from that decision. The agency announced its new instructions Thursday that say Aduhelm is intended only for...

New Alzheimer's Drug Spurs Big Concerns, an Investigation

2 House committees launch inquiry into approval, cost of Biogen's Aduhelm

(Newser) - It was supposed to have been a "cause for celebration," but instead, it's become a "catastrophe in the making." That's Axios' recent take on Aduhelm , the costly new Alzheimer's drug that was approved by the Food and Drug Administration despite major reservations from...

Another Company to Ask FDA to Approve Alzheimer's Drug

Biogen just won approval for its treatment despite experts' dissent

(Newser) - Eli Lilly is nearly ready to take another shot at getting approval for a possible Alzheimer's drug. The drugmaker said Thursday that it plans to submit its potential treatment donanemab to the Food and Drug Administration later this year. The announcement comes a few weeks after the FDA approved...

Cost of Alzheimer's Drug Could Push Medicare to the Brink

Biogen product would nearly double program's medication budget, though it might not work

(Newser) - The Food and Drug Administration's approval of a new drug to treat Alzheimer's disease could have enormous implications not just for patients, but for Medicare—even pushing the program toward collapse. FDA approval historically has meant Medicare will cover the cost of the medication, but with Biogen's...

Alzheimer Drug 'Debacle' Continues With Yet Another Resignation

Aaron S. Kesselheim is 3rd FDA adviser to resign after agency approves Aduhelm

(Newser) - The "debacle" over an Alzheimer's drug recently approved by the Food and Drug Administration continues, or at least that's how the commotion is being described by a third adviser to the agency who's now quit over it. Mayo Clinic neurologist Dr. David Knopman and Washington University...

Reagan's Daughter Has a Fear About Alzheimer's Drug

What if Aduhelm keeps people in an awful state of limbo, asks Patti Davis

(Newser) - Ronald Reagan's daughter is raising a concern about Aduhelm , the first new drug approved to treat Alzheimer's in nearly 20 years. In an essay at USA Today , Patti Davis recalls the "heartbreaking" early stages of her father's disease. He would struggle to come up with a...

FDA Advisers Quit Over Alzheimer's Drug: 'Sham Process'

They're not happy the agency OK'd Biogen's Aduhelm against panel's recommendation

(Newser) - The week kicked off with controversy swirling around aducanumab, the drug being marketed by Biogen as Aduhelm to treat Alzheimer's disease. The drama continues, with two members of an advisory panel to the Food and Drug Administration stepping down over the agency's decision to OK the drug against...

That New Alzheimer&#39;s Drug Costs Way More Than Expected
Analysts Blindsided by Price
of New Alzheimer's Drug
the rundown
Jun 9, 2021 8:35 AM CDT

Analysts Blindsided by Price of New Alzheimer's Drug

A year of Biogen's Aduhelm will run $56K

(Newser) - Monday brought the big news that the FDA had approved the first new Alzheimer’s drug in 20 years. Then came news of its price tag. That would be $56,000 for a year's worth of Aduhelm, also known as aducanumab (a user's out-of-pocket cost would depend on...

FDA Approves Controversial New Alzheimer's Drug

Biogen's aducanumab receives green light, despite questions about effectiveness

(Newser) - Big news in the world of Alzheimer's: The FDA on Monday approved the first new treatment in nearly 20 years, disregarding warnings from independent advisers that the drug hasn't been shown to help slow the brain-destroying disease, per the AP . The drug aducanumab is made by Biogen and...

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