Alzheimer's Disease

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This Could Be a 'Momentous, Historic' Moment in Fight Against Alzheimer's
FDA Approves
Early Treatment
Alzheimer's Drug
updated

FDA Approves Early Treatment Alzheimer's Drug

Drug to be sold as Lequembi has safety concerns, however

(Newser) - A drug found to slow the progression of Alzheimer's disease received federal approval on Friday for patients dealing with mild impairment. Lecanemab was effective in clinical trials but raised safety concerns, and experts say the benefits are not overwhelming, NBC News reports. Nevertheless, the FDA fast-tracked its approval, not...

Scientists Report Success on Blood Test for Alzheimer's

Study suggests procedure could eliminate the need for brain imaging or painful spinal taps

(Newser) - A new blood test has the potential to make it easier, cheaper, and less painful to diagnose Alzheimer's. Researchers writing in the journal Brain say their test fared well in a study involving 600 patients in picking up a telltale marker of brain neurodegeneration, per a news release . A...

Chris Hemsworth Learns of Health Risk While Making Show

Actor has an increased risk for Alzheimer's, he discovers on 'Limitless'

(Newser) - Chris Hemsworth got an unwanted surprise when participating in the National Geographic series Limitless on Disney+. Blood tests revealed that the then-37-year-old Thor star has roughly 10 times the average risk of developing Alzheimer's because both his parents have a gene known as APOE4. "It was initially pretty...

Dementia Clues Appear Almost a Decade Before Diagnosis
Dementia Clues Appear
Almost a Decade
Before Diagnosis
in case you missed it

Dementia Clues Appear Almost a Decade Before Diagnosis

Individuals showing signs of cognitive impairment could be key in treatment trials

(Newser) - Memory loss and cognitive impairment may be detectable up to nine years before an official dementia diagnosis, according to research offering some hope for early intervention. Alzheimer's and dementia are hard to treat, as diagnosis usually comes after symptoms appear, at which point it may be too late to...

After Aduhelm Debacle, New Alzheimer's Drug Emerges

Biogen, partner Eisai: Clinical trial for lecanemab shows promising 27% slowing of cognitive decline

(Newser) - Last year, the FDA approved aducanumab , marketed as Aduhelm , a controversial drug made by Biogen and its Japanese partner Eisai to treat Alzheimer's. Things didn't go well, though, with expert opposition to the costly medication and a final death blow to its place in the market after Medicare...

Suggestions of Fraud Rattle Alzheimer's Research Field

Investigation casts doubt on fundamental work from 2006

(Newser) - In the world of Alzheimer's research, it's a bombshell. A new investigation has raised allegations that landmark research conducted in 2006 was fabricated, reports NBC News . The journal Science is out with a report that casts serious doubt on the work of Sylvain Lesne of the University of...

Young Spinal Fluid Improves Memory in Older Mice
Fight Against Aging
Enters a 'Whole New Era'
NEW STUDY

Fight Against Aging Enters a 'Whole New Era'

Young spinal fluid is seen to improve memory in older mice, per new research

(Newser) - Researchers are heralding "a whole new era" in the search for Alzheimer's treatments, with a new study suggesting those treatments don't necessarily need to address damage in the brain. Tony Wyss-Coray of Stanford University previously showed infusions of blood from younger animals could reverse the effects of...

'Vicious Cycle' Involves Napping, Cognitive Decline
'Vicious Cycle' Involves
Napping, Alzheimer's
NEW STUDY

'Vicious Cycle' Involves Napping, Alzheimer's

Study suggests excessive daytime napping is associated with greater risk for the disease among older adults

(Newser) - Older adults who suddenly find themselves napping longer and more frequently during the day might want to have their brains checked. That's according to researchers at Brigham and Women's Hospital who explored a link between excessive daytime napping and Alzheimer's disease. They analyzed the duration and frequency...

Medicare Makes Big Decision on New Alzheimer's Drug

For now, it will limit Aduhelm coverage to those involved in a clinical trial

(Newser) - Medicare said Tuesday it will limit coverage of a $28,000-a-year Alzheimer’s drug whose benefits have been widely questioned , a major development in the nation’s tug-of-war over the fair value of new medicines that offer tantalizing possibilities but come with prohibitive prices. The initial determination from the Centers...

Maker Cuts Price of Alzheimer's Drug in Half

The medication wasn't catching on at more than $50K per year, Biogen says

(Newser) - Biogen is slashing the price of its Alzheimer's treatment in half, months after it debuted to widespread criticism over an initial cost that could reach $56,000 annually. The drugmaker said Monday that it will cut the wholesale acquisition cost of the drug by about 50% next month. That...

Death Raises New Concern Over Alzheimer's Drug

Critics say Aduhelm approval was rushed

(Newser) - Aduhelm, the Alzheimer’s drug approved this summer in a process that led some FDA advisers to quit , is the subject of new controversy. A 75-year-old woman in Canada participating in a clinical trial died in September after going to the hospital for a seizure, the New York Times reports....

Alzheimer's Vaccine Delivered via the Nose to Be Tested

The vaccine is intended to both prevent Alzheimer's and slow its progress

(Newser) - Dr. Howard Weiner has spent 20 years on research leading up to this moment: the "landmark first human trial" of an Alzheimer's disease nasal vaccine. Sixteen people ranging in age from 60 to 85 will get two doses over the course of two weeks at the Ann Romney...

Cabbies' 'Remarkable Brains' Help Alzheimer's Research

London drivers map routes during MRI scans

(Newser) - The brains of London cabdrivers aren't like other people's. Before they're hired, prospective drivers study the city's streets for years and memorize thousands of routes, the Washington Post reports. And it's not just a matter of remembering information long enough to pass the tests; human...

Cops: Wife Told Husband He Had Alzheimer's, Stole $600K
Cops: Wife Duped Husband for
Years, to the Tune of $600K
in case you missed it

Cops: Wife Duped Husband for Years, to the Tune of $600K

Donna Marino's spouse didn't have Alzheimer's but she made him think he did to control his money

(Newser) - For two decades, a Connecticut man says he let his wife handle virtually all of his finances for him, a move he apparently felt even more necessary once he was diagnosed with Alzheimer's. At least, he thought he'd been diagnosed with Alzheimer's. East Haven police say that'...

2 Health Care Systems Won't Use Aduhelm Yet

Cleveland Clinic, Mount Sinai wait for results of investigation into FDA approval process

(Newser) - Although a new drug for treating Alzheimer's cleared the Food and Drug Administration's approval process, a pair of large health systems say it has not cleared theirs. The Cleveland Clinic and Mount Sinai Health System in New York won't administer Aduhelm to patients until they have more...

FDA Approval of Alzheimer's Drug to Be Reviewed

Agency chief fears damage to public confidence in process

(Newser) - The acting head of the Food and Drug Administration wants the agency's inspector general to conduct an independent review of the agency's approval of a new drug to treat Alzheimer's. The approval process, which one outside adviser had called a "sham" as he resigned, has been...

FDA Walks Back Broad Alzheimer's Drug Advice

After criticism, agency says label will limit candidates to those with mild symptoms

(Newser) - After being widely criticized for approving the use of a new drug to treat all Alzheimer's patients, despite only limited evidence that it works, the Food and Drug Administration has stepped back from that decision. The agency announced its new instructions Thursday that say Aduhelm is intended only for...

New Alzheimer's Drug Spurs Big Concerns, an Investigation

2 House committees launch inquiry into approval, cost of Biogen's Aduhelm

(Newser) - It was supposed to have been a "cause for celebration," but instead, it's become a "catastrophe in the making." That's Axios' recent take on Aduhelm , the costly new Alzheimer's drug that was approved by the Food and Drug Administration despite major reservations from...

Another Company to Ask FDA to Approve Alzheimer's Drug

Biogen just won approval for its treatment despite experts' dissent

(Newser) - Eli Lilly is nearly ready to take another shot at getting approval for a possible Alzheimer's drug. The drugmaker said Thursday that it plans to submit its potential treatment donanemab to the Food and Drug Administration later this year. The announcement comes a few weeks after the FDA approved...

Cost of Alzheimer's Drug Could Push Medicare to the Brink

Biogen product would nearly double program's medication budget, though it might not work

(Newser) - The Food and Drug Administration's approval of a new drug to treat Alzheimer's disease could have enormous implications not just for patients, but for Medicare—even pushing the program toward collapse. FDA approval historically has meant Medicare will cover the cost of the medication, but with Biogen's...

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