Nervous Scientists to Test Stem Cells on Humans

Less-than-positive results could spell disaster
By Evann Gastaldo,  Newser Staff
Posted Aug 30, 2010 11:39 AM CDT
Nervous Scientists to Test Stem Cells on Humans
In this file photo originally made available by Advanced Cell Technology in 2006, a single cell is removed from a human embryo to be used in generating embryonic stem cells for scientific research.   (AP Photo/Advanced Cell Technology)

Scientists are preparing the first human tests of stem cell treatments—and they're nervous about it. They plan to inject cells into patients with spinal cord injuries and progressive blindness, a move that, based on animal trials, should improve the patients' condition. But those involved still fear anything less than positive results will spell disaster for the field, especially after the sudden cut off of federal funding last week. "We desperately need to know how these cells are going to perform in the human setting," one scientist tells the Washington Post. "But are we transplanting cells that are going to cause tumors?"

The trials are privately funded and government-sanctioned, and extensive lab experiments were required by the FDA in advance of using humans. Only adults will be considered, and many precautions are being taken. Even so, "there's a lot of angst around these trials," says another researcher—if stem cells hurt patients, or just do nothing, it could torpedo funding. But "if we're right," says one CEO whose company is studying paralyzed patients, "we'll revolutionize the treatment of many chronic diseases."
(More embryonic stem cells stories.)

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